神经纤维瘤是一种源于皮肤和皮下组织的一种良性肿瘤,生长速度较慢,但也可有阶段性生长加速。神经纤维瘤病是神经嵴细胞分化异常而导致多系统损害的常染色体显性遗传病,累及神经、肌肉、骨骼、内脏和皮肤[1,2],其治疗较为困难,应首选手术切除治疗。但对于巨大神经纤维瘤,手术切 Neurofibroma is a benign tumor of the skin and subcutaneous tissue that grows slowly but can also accelerate in stages. Neurofibromatosis is an autosomal dominant genetic disorder that results from abnormal differentiation of neural crest cells leading to multiple system damage. It involves nerves, muscles, bones, viscera and skin [1, 2]. It is more difficult to treat and should be the first choice for surgical resection. But for huge neurofibromas, surgical resection