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由华大基因和深圳第二医院等单位主导完成的“肠道微生物与Ⅱ型糖尿病的宏基因组关联分析”研究成果,9月27日在《自然》杂志在线发表。该研究为全面揭示Ⅱ型糖尿病与肠道微生物之间的关系奠定了重要的分子基础,为通过DNA序列的微生物分类提供了新方法。该成果同时也体现出基于肠道菌群的关联分析,在糖尿病的临床评定和病人诊断中的应用价值和前景。Ⅱ型糖尿病是一种由遗传和环境因素共同引起的复杂内分泌疾病。研究表明,Ⅱ型糖尿病
The research results of “Meta-analysis of gut microbiomes and type II diabetes mellitus” led by units such as Huada Gene and Shenzhen No. 2 Hospital were published online in Nature on September 27th. This study laid an important molecular foundation for fully revealing the relationship between type 2 diabetes and gut microbes and provided a new method for the classification of microorganisms by DNA sequences. The results also reflect the value and prospects of gut flora-based association analysis in the clinical assessment and patient diagnosis of diabetes. Type II diabetes is a complex endocrine disease caused by genetic and environmental factors. Studies have shown that type II diabetes