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目的分析沙眼衣原体(CT)肺炎患儿的临床表现、实验室检查、影像学检查。方法选取福建医科大学附属泉州第一医院2015年1月—2016年1月收治的CT肺炎患儿88例,患儿入院后均给予对症支持治疗及抗生素治疗,回顾性分析其临床表现、实验室检查、影像学检查及治疗结果。结果 CT肺炎好发于年龄<3个月婴儿,发生率为87.5%,3~6个月患儿发病率为11.4%,>6个月患儿发病率为1.1%。咳嗽为CT肺炎患儿的最主要临床表现,其次为气促、肺部湿啰音、吸气性三凹征、气喘,患儿中均经检查显示CT-DNA阳性,淋巴细胞分数升高患儿占75%,白细胞计数升高患儿占30.68%,凝血功能异常患儿占5.68%。治疗后,患儿临床症状、体征2周内消失68例,占77.27%,2周~1个月消失12例,占1.64%,2~6个月消失6例,占6.82%,>6个月消失1例,占1.14%,治疗2周自动出院3例,2例合并金黄色葡萄球菌,1例合并巨细胞病毒感染,均失访,占3.41%。结论CT是儿童尤其是婴幼儿感染的重要病原体,大环内酯类抗感染治疗有效,部分病例症状可持续存在,需引起重视。
Objective To analyze the clinical manifestations, laboratory tests and imaging examination of children with Chlamydia trachomatis (CT) pneumonia. Methods 88 patients with CT pneumonia admitted to Quanzhou First Hospital Affiliated to Fujian Medical University from January 2015 to January 2016 were enrolled. All patients were given symptomatic supportive therapy and antibiotic treatment after admission. The clinical manifestations were retrospectively analyzed. The laboratory Inspection, imaging examination and treatment results. Results CT pneumonia occurred in infants <3 months, the incidence was 87.5%. The incidence of infants in 3 ~ 6 months was 11.4% and the incidence of infants in 6 months was 1.1%. Cough is the most important clinical manifestation in children with CT pneumonia, followed by shortness of breath, wet lung sound in the lungs, three concave signs in the inspiratory tract, asthma and children with positive CT-DNA and elevated lymphocyte score Accounted for 75% of children, children with elevated white blood cell count accounted for 30.68%, children with coagulation dysfunction accounted for 5.68%. After treatment, 68 cases (77.27%) disappeared within 2 weeks after the treatment, 12 cases disappeared in 2 weeks to 1 month (1.64%), 6 cases disappeared in 2 to 6 months (6.82%, 6) Month disappeared in 1 case, accounting for 1.14%. 3 cases were discharged automatically after 2 weeks of treatment, 2 cases were infected with Staphylococcus aureus, and 1 case was infected with cytomegalovirus. Conclusion CT is an important pathogen of infection especially in infants and toddlers in children. Macrolide anti-infective therapy is effective and the symptoms of some cases can persist, which needs attention.