AGES相关论文
【目的】本课题观察新型降糖药GLP-1类似物利拉鲁肽（Liraglutide,Li）对1型糖尿病大鼠认知功能障碍的改善作用,并研究该作用与AGEs-RA......
目的:本课题应用D-半乳糖致衰老大鼠模型,以艾炷灸关元、命门穴为干预手段,通过测定各组大鼠脑组织中晚期糖基化终末产物（advance d......
第一部分靶向线粒体氧化应激对AGEs诱导髓核细胞凋亡的作用及机制研究目的:探讨线粒体途径在AGEs诱导NP细胞凋亡过程中的作用机制,......
背景糖尿病时,心肌微血管损伤往往发生在大血管及心肌细胞损伤之前,是糖尿病心肌结构与功能障碍的重要始发因素之一,也是导致糖尿......
目的 观察AGEs调节NF-κB通路对软骨细胞炎症因子IL-1β表达的影响.方法 将软骨细胞传代培养,取对数生长的软骨细胞接种于96孔板,......
研究目的:通过观察生酮饮食（Ketogenic diet,KD）干预糖尿病小鼠认知障碍改善的效果,探讨其可能的分子机制,为KD在糖尿病认知障碍（Diab......
Comparative Transcriptome Analysis druing skeletal muscle postnatal development in Bovines of Differ
Gender and slaughter age are two key pre-slaughter variables that can significantly affect the skeletal muscle developme......
Advanced glycation end products promote TNF-a expression in T lymphocyte via p38、JNK and NF-κB signa
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D-Ribose, an important reducing monosaccharide, is highly active in the glycation of proteins, and results in the rapid ......
RESEARCH ON EFFECT OF AGEs-RAGE SIGNALING PATHWAY ON MYOCARDIAL FIBROSIS OF TYPE TWO DIABETIC RATS A
Diabetic cardiomyopathy (DCM) is one of the chronic complications of diabetes mellitus (DM), and it is one of the main r......
Aim of study:Fu Fang Zhen Zhu Tiao Zhi formula (FTZ),for which a patent has been issued,is composed of eight medical her......
The Factors Resulted in Drug Resistance in Plamodium falciparum Infection Therapy-A Systematic Revie
Objectives: To generate pooled analyses to understand the impact of inadequate drugs in key subpopulations,and to provid......
目的 探讨慢性阻塞性肺疾病患者血浆sRAGE与AGEs水平变化及意义 方法 选取我院80例慢阻肺患者与80例健康对照者，分别测量其血浆sRAG......
Advanced glycation end products (AGEs), products of the irreversible reaction of carbohydrates and protein in the Mailla......
Study on the Mechanism of Active Component in Radix Rehmanniae and Cornus officinalis for Regulating
Object:Diabetes nephropathy (DN) is the typical diabetic complication.It includes glomerular mesangial cell proliferatio......
A series of novel diosmetin derivatives was designed and synthesized using rational drug-design principles....
Advanced glycation end products (AGEs) are a heterogeneous group of proteins that have been modified with glucose or car......
Beijinger’s understanding and pride to the Grand Canal originated from the section between Baifu Spring in Changping Di......
晚期糖基化终末产物(Advanced Glycation End-products,AGEs)是蛋白质、氨基酸等大分子物质在非酶促条件下经美拉德反应形成的化学......
The astronomical theory of climate change is based on the solution of differential equations describing Earth’s orbital......
糖尿病肾病(diabetic nephropathy,DN)是糖尿病常见而严重的微血管并发症,由血糖、糖化终产物(advancedglycation end-products,AG......
目的:晚期糖基化终产物(AGEs)在许多糖尿病的并发症及衰老的发生发展中起着十分重要的作用。本研究目的是探讨晚期糖基化终产物(AG......
AIM:To study the formation of intracellular glyceraldehyde-derived advanced glycation end products(Glycer-AGEs)in the pr......
Non-alcoholic fatty liver disease(NAFLD)is a major cause of liver disease around the world.It includes a spectrum of con......
目的 观察不同病程的糖尿病大鼠肾组织内糖基化终产物受体(RAG)mRNA的表达水平的改变。方法 采用逆转录聚合酶链式反应(RT-PCR)检......
The LA-ICP-MS zircons U-Pb ages and geochemistry of the Baihua basic igneous complexes in Tianshui a
Baihua meta-igneous complex consists mainly of pyroxenite-gabbro(diorite)-diorite-quartz diorite. They form a complete c......
New 40Ar/39Ar plateau ages from rocks of Changle-Nanao ductile shear zone are 107.9 Ma(Mus), 108.2 Ma(Bi), 107. 1 Ma(Bi)......
传统单一降糖存在严重误糖尿病患者都知道:高血糖并不可怕,可怕的是由糖尿病所引起的各种并发症。糖尿病的主要危害是危及生命的多......
1.糖化蛋白葡萄糖、果糖等还原糖可与蛋白质赖氨酸残基ε氨基结合,这种非酶反应下与糖结合的蛋白叫做糖化蛋白。糖化与蛋白质发生......
自从使用胰岛素以来,糖尿病急性并发症的发生率和死亡率已明显降低,而糖尿病慢性并发症已成为威胁糖尿病人生命和生活能力的主要......
动脉粥样硬化(As)已成为糖尿病患者的常见并发症和主要致死致残原因。持续的高血糖可使体内结构和功能蛋白质被糖基化修饰,形成有......
目的:观察绞股蓝皂苷(GP)对晚期糖基化终末产物(AGEs)诱导的人肾小球系膜细胞(HMCs)增殖及分泌细胞外基质(ECM)的影响。方法:将对......
Rosiglitazone inhibits expression of acyl-coenzyme A:cholesterol acyltransferase-1 in THP-1 macropha
Objective:To investigate the effects of rosiglitazone,a synthetic ligand of peroxisome proliferators-activated receptor ......
糖尿病微血管病变以血管基底膜增原为主要病理特征，其发生的机理尚不明确，而Ⅳ型胶原是血管基底膜的主要成分之一。我们将体外培养的......
糖尿病是常见病和多发病，其血管病变则是该病主要致残、致死原因。随着机体衰老，非酶糖基化随之增加，糖基化终产物（AGEs）可在组织中不断......
Effects of Total Flavonoids in Drynaria fortunei (Kunze)J. Sm. on Osteoblasts Differentiation and Ex
[Objective] To observe the effects of total flavonoids in Drynaria fortunei (Kunze) J. Sm. (TFDF) on osteoblasts (OB) di......
糖尿病性视网膜病变 (diabetic retinopathy,DR)和糖尿病性白内障 (diabetic cataract,DC)是糖尿病(diabetic mellitus,DM)的两大......
为观察高糖、晚期糖化终产物(AGEs)对体外培养的小鼠心脏微血管内皮细胞血管细胞粘附分子 1(VCAM 1)表达的影响 ,分离、培养小鼠心......
目的 观察糖基化终末产物 (AGEs)对破骨细胞骨吸收功能的影响。方法 用人血清白蛋白和葡萄糖恒温孵育制备人AGEs,采用甲苯胺蓝染......
肾脏病变是糖尿病主要的微血管病变 ,它的病理变化表现为肾小球基底膜增厚、肾小球肥大、基质增生及以后发展的肾小球硬化和肾小球......
糖尿病视网膜病变 (diabeticretinopathy ,DR)是糖尿病最常见、最严重的一种慢性并发症。是成人后天性致盲的主要原因。日本的一组......
目的研究皮肤组织中细胞外基质(ECM)成分的糖基化对成纤维细胞(FB)黏附增殖能力的影响。方法对糖尿病患者皮肤组织中晚期糖基化终......
糖化终末产物(AGEs)受体(RAGE)通过与AGEs相互作用,激活一些关键的细胞信号传递途径,产生一系列病理损伤反应,参与糖尿病血管并发......
