系统性红斑狼疮 (ＳＬＥ)并发肾脏疾病的发生率高 ,但狼疮性肾炎 (ＬＮ)并发脑病的发生率并不高 ,一旦发生 ,来势凶险 ,预后极差。单一用肾上腺皮质激素治疗可改善病情 ,但大部分患者对治疗反映差。近年来 ,国内外很多学者采用甲基强的松龙和环磷酰胺联合冲击治疗 ,明显提高疗 The incidence of systemic lupus erythematosus (SLE) complicated with kidney disease is high, but the incidence of lupus nephritis (LN) complicated with encephalopathy is not high. Once it occurs, it is dangerous and the prognosis is extremely poor. Single adrenocorticotropic hormone treatment can improve the condition, but most patients respond poorly. In recent years, many scholars at home and abroad using methylprednisolone and cyclophosphamide combined impact treatment, significantly improve the treatment