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目的探讨睾丸硬化型支持细胞瘤的临床病理和生物学特点。方法对1例睾丸硬化型支持细胞瘤进行组织形态学、超声诊断学和免疫组化研究,并复习相关文献。结果患者男性,38岁。无意间发现左侧阴囊内一肿块,质硬、无痛。超声提示左侧睾丸下极低回声占位。组织学表现为片状、条索状、实性小管状结构,由丰富致密的纤维间质分隔,肿瘤细胞无明显异型。免疫组化:vimentin(+),CKpan、inhibin-α、S-100、CD68和calretinin(-)。结论睾丸支持细胞瘤是一种少见的肿瘤,其中硬化型亚型的临床及病理学表现较非特殊类型及大细胞钙化型更为独特,一般无复发或转移,是一种恶性潜能极低的亚型。
Objective To investigate the clinicopathological and biological features of testicular sclerosing soma. Methods One case of testicular sclerosing hematopoietic tumor was studied by histomorphology, ultrasonography and immunohistochemistry, and the related literatures were reviewed. Results The patient was male, 38 years old. Inadvertently found a mass within the left scrotum, hard, painless. Ultrasound prompts low echo of the left testes placeholder. Histological manifestations of lamellar, cordlike, solid small tubular structure, separated by a rich and dense fibrous stroma, tumor cells without significant dysplasia. Immunohistochemistry: vimentin (+), CKpan, inhibin-α, S-100, CD68 and calretinin (-). Conclusion Sertoli cell tumor is a rare tumor in which the clinical and pathological features of sclerosing subtype are more unique than non-special type and large cell calcification, and generally have no recurrence or metastasis. It is an extremely malignant potential Subtype.