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目的探讨2型糖尿病(T2DM)患者睡眠质量及其对血糖控制的影响。方法 114例就诊的2型糖尿病患者,采用匹兹堡睡眠质量指数量表(PSQI)调查2型糖尿病患者具体睡眠质量,PSQI评分≤7分为睡眠良好组(56例),PSQI评分>7分为睡眠障碍组(58例)。睡眠障碍组根据治疗方法的不同分为常规治疗组和综合治疗组,每组29例。常规治疗组采用日常规范制度进行有效治疗,综合治疗组采用综合的临床方法进行治疗。分析两组患者临床相关资料及血糖指标。结果睡眠良好组与睡眠障碍组患者的性别、年龄、体质量指数(BMI)及病程对比差异无统计学意义(P>0.05)。睡眠良好组与睡眠障碍组的最大血糖波动幅度(LAGE)、空腹血糖变异系数(CV-FBG)、糖化血红蛋白(Hb A1c)、血糖标准差(SDBG)、空腹血糖(FBG)、平均血糖水平(MBG)比较,差异有统计学意义(P<0.05)。常规治疗组与综合治疗组治疗后PSQI评分及血糖指数较治疗前均有所下降,且综合治疗组患者的FBG、CVFBG、LAGE、Hb A1c、MBG均低于常规治疗组(P<0.05);常规治疗组与综合治疗组治疗后的SDBG比较,差异无统计学意义(P>0.05)。治疗后综合治疗组的PSQI评分为(6.31±0.97)分,优于常规治疗组的(8.34±1.45)分(P<0.05)。结论睡眠障碍为2型糖尿病的严重问题,患者因无法正常入睡导致2型糖尿病的血糖逐渐上升无法正常下降、患者血糖变动也随之渐渐增高。血糖改变对2型糖尿病患者有效睡眠有非常重要的辅助作用,而干预睡眠障碍能够改善睡眠质量,同时可以帮助控制血糖。
Objective To investigate the quality of sleep and its effect on glycemic control in type 2 diabetes mellitus (T2DM). Methods A total of 114 patients with type 2 diabetes mellitus were enrolled in this study. The Pittsburgh Sleep Quality Index Scale (PSQI) was used to investigate the specific sleep quality in patients with type 2 diabetes. PSQI score ≤ 7 was assigned to sleep well (n = 56) and PSQI score> 7 Disorder group (58 cases). Sleep disorders group according to the different treatment methods are divided into conventional treatment group and comprehensive treatment group, 29 cases in each group. The conventional treatment group used the daily standard system for effective treatment, and the comprehensive treatment group used the comprehensive clinical method for treatment. Analysis of two groups of patients clinically relevant information and blood glucose indicators. Results There was no significant difference in sex, age, body mass index (BMI) and course of disease between the sleep good group and the sleep disturbance group (P> 0.05). The values of maximum blood glucose fluctuation (LAGE), CV-FBG, Hb A1c, SDBG, FBG and mean blood glucose level in sleep-good group and sleep- MBG), the difference was statistically significant (P <0.05). PSQI score and glycemic index decreased after treatment in both the conventional treatment group and the comprehensive treatment group, and the FBG, CVFBG, LAGE, Hb A1c and MBG in the combined treatment group were lower than those in the conventional treatment group (P <0.05). There was no significant difference in SDBG between conventional treatment group and comprehensive treatment group (P> 0.05). The PSQI score of the combined treatment group was (6.31 ± 0.97) points after treatment, which was significantly higher than that of the conventional treatment group (8.34 ± 1.45) (P <0.05). Conclusions Sleep disorders are a serious problem of type 2 diabetes. Patients unable to fall asleep normally lead to the gradual rise of blood glucose of type 2 diabetes patients, and their blood glucose changes gradually increase. Changes in blood glucose in patients with type 2 diabetes effective sleep has a very important role in the intervention, and sleep disorders can improve sleep quality, and can help control blood sugar.