一、狂犬病疫苗简介狂犬病是人被疯动物咬伤而传染的一种严重传染病。人被疯动物咬伤后大约1/3发病,一旦发病均致死。目前控制狂犬病最有效措施是预防。首先是管理好家犬,切断传染源,其次是防止发病。人被疯动物咬伤后应立即接种狂犬疫苗。介绍几种主要的疫苗: (一)狂犬病脑组织疫苗:1884年巴斯德氏创立了用动物脊髓组织制备疫苗,次年应用于临床,至今已近一百年,在制备方法上不断改进,有许多改良脑组织疫苗如山蒲氏疫苗等,这些疫苗的预防效果是肯定的,但因含有髓磷脂,接种后可引起严重的神经系统变态反应。为了减少或除去疫苗中的变态反应原,采用了乳动物的组织疫苗,或用理化方法除去脑组织等,但成效不大。50年 First, the rabies vaccine Introduction Rabies is a bite of mad animals and transmission of a serious infectious disease. About a third of the people were attacked by bingo animals and died in the event of a disease. Currently the most effective measure to control rabies is to prevent it. The first is to manage domestic dogs, cut off the source of infection, followed by prevention of morbidity. Rabbit vaccination should be immediately after being bitten by mad animals. Introduction to several major vaccines: (1) rabies brain vaccine: Pasteur established in 1884 to use animal spinal cord tissue preparation vaccine, the following year for clinical use, has been nearly a hundred years, continuous improvement in the preparation method, There are many improvements in brain tissue vaccines such as Aspergillus flavus vaccine, the preventive effect of these vaccines is positive, but because of myelin, vaccination can cause serious nervous system allergy. In order to reduce or eliminate the allergens in the vaccine, the use of tissue vaccine of dairy animals, or physical and chemical methods to remove brain tissue, but with little success. 50 years