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:目的 进一步阐明胰岛素抵抗 (IR)与脑梗塞及其程度的关系 ,探讨不同方法学对结果的影响 .方法 用胰岛素敏感性指数 (ISI)及胰岛素曲线下面积 (AIC)两种方法判断 46例脑梗塞患者的 IR状态 ,并将两种方法与病情进行了比较 .结果 脑梗塞患者的 ISI显著低于对照组 ,AIC显著大于对照组 ,且与临床病情轻重密切相关 .AIC方法敏感于 ISI方法 .结论 IR与脑梗塞关系密切 ,可能在脑梗塞发病中起重要作用
: Objective To further elucidate the relationship between insulin resistance (IR) and cerebral infarction and its extent, and to explore the influence of different methodologies on the outcome.Methods 46 patients with insulin resistance (ISI) and the area under the curve of insulin (AIC) Cerebral infarction patients IR status and the two methods were compared with the disease.Results ISI in patients with cerebral infarction was significantly lower than the control group, AIC was significantly greater than the control group, and closely related to the severity of clinical conditions.AIC method is sensitive to the ISI method .Conclusion IR is closely related to cerebral infarction and may play an important role in the pathogenesis of cerebral infarction