用内径为0.30mm的银夹钳夹双侧肾动脉,复制出一种易卒中型肾血管性高血压大鼠模型,其血压峰值高且稳定在26.7kPa以上,并发生与人类高血压病类似的脑动脉损害:细小动脉纤维素样坏死、透明变性和微动脉瘤形成等,在此基础上,0.56的大鼠自发产生各种类型的脑卒中:脑梗塞、脑出血、蛛网膜下腔出血和混合性脑卒中。本文还着重将这种易卒中型肾血管性高血压大鼠与易卒中型自发性高血压大鼠作了比较。 Bilateral renal arteries were clipped with a silver clamp with an inner diameter of 0.30 mm and a rat model of stroke-prone renovascular hypertension was replicated with a high peak and stable blood pressure above 26.7 kPa and similar to that of human hypertension Cerebral Arterial Lesions: Fine Arterial Cellulose-like Necrosis, Transparent Degeneration and Aneurysm Formation, etc. On this basis, 0.56 rats spontaneously develop various types of stroke: cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage And mixed stroke. This article also focuses on the stroke-prone renovascular hypertensive rats and stroke-prone spontaneously hypertensive rats were compared.