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通过检测丙型肝炎抗体与丙型肝炎病毒(HCV)核糖核酸的方法对广东地区442例慢性乙型肝炎病毒(HBV)感染者发生HCV重叠感染的状况进行流行病学调查,分析其与输血及血制品的关系。结果显示慢性HBV感染患者中HCV重叠感染率为9.73%;其发生主要与治疗性输用血浆有关。与不输血制品相比,输白蛋白、输血浆和输血浆加白蛋白引起HCV重叠感染的相对危险度分别为2.13,122.57和125.84。而且血浆输入量越大,发生重叠感染的危险性也越大。当输注血浆超过16次,重叠感染率可达77.78%
The prevalence of HCV over-infection in 442 cases of chronic hepatitis B virus (HBV) infection in Guangdong area was investigated by detecting hepatitis C virus and hepatitis C virus (HCV) RNA. The relationship between blood products. The results showed that the prevalence of HCV infection in patients with chronic HBV infection was 9.73%. The incidence of HCV infection was mainly related to therapeutic transfusion of plasma. Compared with non-blood transfusion products, the relative risk of overlapping infection of albumin, transfusion plasma and plasma albumin plus albumin were 2.13, 122.57 and 125.84, respectively. And the greater the plasma input, the greater the risk of overlapping infections. When the infusion of plasma more than 16 times, the overlap rate of up to 77.78%