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Diagnostic value of serumal level of proinflammatory(TNF-α,IL-1β,IL-6 and IFN-γ)and anti-inflammatory(IL-4 and IL-10)cytokines of immune system is investigated at 54 mammary glands sick by a cancer.The analysis carried out has allowed to tap the raised concentration of such proinflammatory cytokine,ss IL-1β,TNF-α and IL-6 in serum of peripheric blood of MGC patients.The analysis of antiinflammatory cytokines in Serum of peripheric blood of MGC patients also has taped authentically raised value of IL-4 and IL-10.The obtained data testify to presence imbalance cellular and humoral factors of the immune system which studying will serve as the important diagnostic criterion of breast cancer.