论文部分内容阅读
目的 :探讨女阴尖锐湿疣及假性湿疣的临床病理诊断和鉴别诊断依据。方法 :收集 2 97例患者的临床资料 ,观察尖锐湿疣及假性湿疣临床和病理学特点 ,部分病例做免疫组化人乳头瘤病毒检测。结果 :真假湿疣发病年龄高峰差异不大。部位 :尖锐湿疣多为两个以上部位同时发生 ,而假性湿疣多数只限于一个部位。局部表现 ,两种病变均形成乳头状突起 ,是临床误诊原因之一 ,但尖锐湿疣常融合成菜花状。组织学观察 ,鳞状上皮乳头状增生及诊断性空泡细胞是尖锐湿疣的主要诊断依据 ,假性湿疣中非诊断性空泡化细胞是病理诊断误诊原因之一。免疫组化染色 ,尖锐湿疣细胞核阳性率为 6 3 % ,假性湿疣为阴性。结论 :诊断性空泡细胞及人乳头瘤病毒检测阳性是目前诊断尖锐湿疣和鉴别假性湿疣的重要依据
Objective: To investigate the clinical and pathological diagnosis and differential diagnosis basis of female genital warts and pseudocondyloma. Methods: The clinical data of 2 97 patients were collected. The clinical and pathological features of condyloma acuminatum and pseudotumorous condyloma were observed. In some cases, immunohistochemistry of human papillomavirus was performed. Results: The incidence of genital warts age difference is not significant. Location: Condyloma mostly for more than two parts of the same time, while the majority of false condyloma is limited to one site. Local performance, the formation of both papillary papillary processes, is one of the reasons for clinical misdiagnosis, but the genus Condyloma often melon-like synthesis. Histological observation, squamous papillary hyperplasia and diagnosis of vacuolar cells are the main basis for the diagnosis of genital warts. The non-diagnostic vacuolar cells in pseudogonia are one of the reasons for the misdiagnosis of pathological diagnosis. Immunohistochemical staining, condyloma acuminata nucleus positive rate of 63%, pseudohypertrophic was negative. Conclusion: Positive detection of diagnostic vacuolar cells and human papillomavirus is an important basis for the diagnosis of condyloma acuminata