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[目的]观察裴瑞霞加味二冬汤联合西药治疗肺肾气阴亏虚型2型糖尿病疗效。[方法]使用随机平行对照方法,将80例住院患者按随机数字表法随机分为两组,均保持糖尿病饮食、运动、生活规律,降压、降糖、扩冠等常规治疗,停用治疗本病的其他中药及一般预防性用药,两组间用药基本保持平衡。对照组40例吡格列酮胶囊、二甲双胍肠溶片常规西药降糖。治疗组40例在对照组基础上给予加味二冬汤(天冬、麦冬、天花粉各15g,黄芩6g,知母12g,甘草10g,北沙参15g,荷叶10g)1剂/d,水煎服,早晚分服。观测空腹血糖(FPG)、餐后2小时血糖(2hPG)、糖化血红蛋白(HbAlc)。均连续治疗3个月为1疗程。连续治疗1疗程,判定疗效。[结果]治疗组临床控制0例,显效27例,有效9例,无效4例,总有效率90.00%。对照组临床控制0例,显效12例,有效13例,无效15例,总有效率62.50%。治疗组疗效优于对照组(P<0.01)。两组FBG,2hPG,HbAlc均明显降低(P<0.01),组间无明显差异(P>0.05)。[结论]加味二冬汤对治疗肺肾气阴亏虚型2型糖尿病疗效满意。
[Objective] To observe the therapeutic effect of Pei Ruixia Jia Wei Er Dong Decoction combined with western medicine in the treatment of type 2 diabetes with deficiency of lung, kidney, yin and yin. [Methods] Eighty patients were randomly divided into two groups according to the random number table method. All the patients were treated routinely with diabetes diet, exercise, daily life, blood pressure, hypoglycemic, The disease of other traditional Chinese medicine and general preventive medication, medication between the two groups to maintain the basic balance. Control group, 40 cases of pioglitazone capsules, metformin enteric-coated conventional western medicine hypoglycemic. 40 cases in the treatment group were given Jia Wei Er Dong Decoction (15g of Asparagus, Ophiopogon japonicus and TCS, 6g of Radix Scutellariae, 12g of Anemarrhena asiaticum, 10g of Radix Aconiti Preparata, 10g of Radix Aconiti Preparata, 15g of Radix Isatidis and 10g of lotus leaf) on the basis of the control group, Decoction, morning and evening service. Fasting blood glucose (FPG), 2 hours postprandial blood glucose (2hPG), HbAlc were observed. Continuous treatment for 3 months for a course of treatment. Continuous treatment of a course of treatment to determine the efficacy. [Results] The clinical control in the treatment group 0 cases, markedly effective in 27 cases, effective in 9 cases, ineffective in 4 cases, the total effective rate was 90.00%. Control group 0 cases of clinical control, markedly effective in 12 cases, effective in 13 cases, 15 cases, the total effective rate was 62.50%. The treatment group than the control group (P <0.01). FBG, 2hPG and HbAlc in both groups were significantly decreased (P <0.01), no significant difference between the two groups (P> 0.05). [Conclusion] Jia Wei Er Dong decoction is effective in treating type 2 diabetes with deficiency of qi and lung of lung and kidney.