【摘 要】
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In recent years, many investigations have indicated that environmental endocrine disruptors (EEDs) may accelerate the development of obesity[1]. One kind of EEDs, di-(2-ethylhexyl) phthalate (DEHP), is ubiquitous in natural environments due to its role in
【机 构】
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Department of Environmental and Occupational Health,School of Public Health,Xinxiang Medical Univers
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In recent years, many investigations have indicated that environmental endocrine disruptors (EEDs) may accelerate the development of obesity[1]. One kind of EEDs, di-(2-ethylhexyl) phthalate (DEHP), is ubiquitous in natural environments due to its role in the manufacture and use of plastic products[2]. Recent research has shown that there are many harmful effects from the accumulation of DEHP in the body, especially in adipose tissue due to its lipid solubility. For example, a recently study indicated that DEHP promotes lipid peroxidation in rat liver[3]. So there is concern about its potential hepatotoxic effects. It is also reported to have lipid metabolism-disrupting effects on adult male animals. Therefore, an understanding of the relationship between phthalates and lipid metabolism disorder in men is urgently needed, and will help to elucidate the causes of obesity in men.
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