Striatum相关论文
3-Nitropropionic acid modifies neurotrophin mRNA expression in the mouse striatum:18S-rRNA is a reli
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The striatum and globus pallidus are principal nuclei of the basal ganglia.Nissl-and acetylcholinesterase-stained sectio......
Using a silicon based implantable microelectrode array to evaluate striatal dopamine release and neu
Subthalamic nucleus deep brain stimulation(STN DBS)ameliorates motor symptoms of Parkinsons disease,but the precise mech......
Behavior deficits and region specific alterations in local field potential oscillations in APP/PS1 m
Alzheimers disease(AD)is the leading cause of dementia,estimated to affect more than 30 million individuals worldwide....
Parkinsons disease(PD)is a progressive neurodegenerative movement disorder that is caused predominantly by the degenerat......
Increased association of the adenosine A2A receptor and dopamine D2 receptor heterodimers after rand
Striatal adenosine A2A receptors(A2ARs)modulate striatal synaptic plasticity and instrumental learning,possibly by funct......
Objective: Motor fatigue is a ubiquitous phenomenon following physical exercises,which involves not only changes of musc......
Dopaminergic differential regulation of beta oscillatory dynamics through modulation of Kir channels
Objective The dorsal striatum plays a key role in motion function and disease,psychiatric disorders.Proper functioning o......
Gene expression profile of 100 Hz electro-acupuncture treatment in 6-hydroxydopamine-induced Parkins
Electro-acupuncture (EA), especially high-frequency EA, has been frequently used as an alternative therapy for Parkinson......
Preferential hemeoxygenase 1 activation in striatal astrocytes antagonized dopaminergic neurons dege
Parkinsons disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc......
We examined cortical plasticity in addicted human subjects and rats following Meth selfadministration(SA).We identified ......
OBJECTIVE The high prevalence of sleep disturbance has been found in patients with striatum-related neurodegenerative di......
Lesion of the locus ceruleus aggravates dopaminergic neuron injury by modulating microglial function
Parkinsons disease (PD) is considered to have selective cell loss of dopaminergic neurons in the substantia nigra (SN).I......
ASIC1a channels contribute to dendritic spine development of striatal medium spiny neurons (MSNs) an
Acid-sensing ion channel la (ASIC1a) is widely expressed in nervous systems, contributing to synaptic activity, learning......
A long-standing question in how the nervous system processes information is whether patterns of action potentials (APs),......
The prefrontal cortex (PFC) and the striatum have mutual connections through direct and indirect pathways. Despite their......
Changes of dopamine transporter function in striatum during acute morphine addiction and its abstine
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M_(4) muscarinic receptors regulates dopamine/DARPP-32 signaling and glutamate transmis⁃sion to bala
OBJECTIVE Abnormal striatal dopaminergic and glutamatergic neurotransmis⁃sion is central to the pathophysiology of schi......
Single Exposure to Cocaine Impairs Reinforcement Learning by Potentiating the Activity of Neurons in
Plasticity in the glutamatergic synapses on striatal medium spiny neurons (MSNs) is not only essential for behavioral ad......
Medium spiny neurons(MSNs)in the striatum,which can be divided into D1 and D2 MSNs,originate from the lateral ganglionic......
Ginsenoside Rg1 exerts neuroprotective effects in 3-nitropronpionic acid-induced mouse model of Hunt
Huntington\'s disease (HD) is one of main neurodegenerative diseases,characterized by striatal atrophy,involuntary mov......
Medium spiny neurons(MSNs)in the striatum,which can be divided into D1 and D2 MSNs,originate from the lateral ganglionic......
The zinc finger transcription factor Sp9 is required for the development of striatopallidal projecti
Striatal medium-sized spiny neurons(MSNs),composed of striatonigral and striatopallidal neurons,are derived from the......
帕金森病是世界第二大老年神经退行性疾病，致病机理极为复杂。α-synuclein（α-syn）是帕金森病主要病理特征的路易小体的主要组成成分......
目的观察吗啡条件性位置偏爱(conditioned place preference，CPP)大鼠纹状体中多巴胺(DA)递质和多巴胺D2受体的同步变化，从神经递质......
目的研究健脾止动汤对多发性抽动症(Tourette syndrome，TS)模型小鼠抽动行为及纹状体内氨基酸递质的影响，探讨健脾止动汤的作用机制......
目的探讨中药健脾止动汤对多发性抽动症(Ts)模型鼠脑内纹状体的多巴胺D2受体(DAD2R)mRNA的影响，为健脾止动汤治疗小儿多发性抽动症......
目的观察慢性酒精暴露后Wistar大鼠不同戒断时间点纹状体NMDA受体2B亚基(NMDA receptor 2B subunit，NR2B)表达的变化。方法72只雄性......
We previously reported that intranasal insulin protects substantia nigra dopaminergic neurons against6-hydroxydopamine n......
目的：通过对抑郁模型大鼠的快速眼动睡眠剥夺，观察大鼠强迫游泳不动时间及大鼠纹状体5-羟色胺、多巴胺和腺苷水平的变化，了解睡眠剥夺......
目的 探讨早期应激对背侧纹状体多棘神经元发育的影响.方法 通过改变新生小鼠(出生后第2～9天)的生长环境建立早期应激动物模型,采用......
A Spatial Cognitive Model that Integrates the Effects of Endogenous and Exogenous Information on the
Reproducing the spatial cognition of animals using computational models that make agents navigate autonomously has attra......
Protective effect of alpha-synuclein knockdown on methamphetamine-induced neurotoxicity in dopaminer
The over-expression of α-synuclein is a major factor in the death of dopaminergic neurons in a methamphetamine-induced ......
目的 研究巴曲酶对黑质纹状体通路损伤的保护作用及可能机制.方法 制备小鼠黑质纹状体通路损伤模型并给予巴曲酶腹腔注射,采用行为......
Effects of Electroacupuncture on Metabolic Changes in Motor Cortex and Striatum of 6-Hydroxydopamine
Objective: To explore the possible underlying mechanism by investigating the effect of electroacupuncture (EA) treatment......
The human striatum is essential for both lowand high-level functions and has been implicated in the pathophysiology of v......
目的:研究甲基苯丙胺(Methamphetamine,MA)对大鼠纹状体中炎性因子肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)、白细胞介......
目的:通过大鼠血浆及纹状体组织匀浆中罗匹尼罗的液相色谱-质谱联用(LC-MS/MS)检测方法,研究其在血浆和纹状体的药动学特征。方法:......
,Blockade of mGluR5 in the nucleus accumbens shell but not core attenuates heroin seeking behavior i
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Parkinson’s disease (PD) is a progressive neurodegenerative disease,which causes a tremendous socioeconomic burden.PD p......
The role of the TrkB-T1 receptor in the neurotrophin-4/5 antagonism of brain-derived neurotrophic fa
This manuscript reviews the function and fundamental characteristics of the neurotrophins and their receptors to introdu......
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Changes of dopamine transporter function in striatum during acute morphine addiction and its abstine
Background Although dopamine transporter (DAT) is essential for addiction, the effect of additive drugs on DAT function ......
目的 研究Wistar大鼠纹状体定向注射TaClo后其行为学改变及黑质中cox-2的表达及其意义.方法 采用立体定向注射技术将TaClo注射到大......
分析强迫症患者皮质‐纹状体‐丘脑‐皮质环路可能存在的神经通路异常，应用功能磁共振成像技术，对强迫症患者的双侧前额叶、海马旁回......
目的探讨大鼠缺血-再灌注损伤模型脑白质弥散张量成像(diffusion tensor imaging，DTI)与行为学的变化联系。方法健康成年SD大鼠根据......
目的:探讨纹状体细胞外液中多巴胺(DA)及其代谢产物在电针抗脑缺血再灌注损伤中的作用.方法:将50只雄性SD大鼠随机分为正常组、假......
