消化性溃疡是指胃肠黏膜被胃酸和胃蛋白酶等自身消化而发生的溃疡,其深度达到或穿透黏膜肌层,最常见于胃溃疡和十二指肠溃疡,消化性溃疡(溃疡病)是一种常见的慢性疾病。我国文献报道,胃镜检查病例中消化性溃疡的检出率高达16%~33%。随着胃镜的广泛开展,其容易诊断,治疗相对规范,但有反复发作的特点,所以溃疡病完全愈合的研究越来越受临床医生的重视,目前采用抑酸药物维持治疗是预防消化性溃疡复发的主要措施,但对维持治疗方案的选择、治疗时间无统一意见。 Peptic ulcer refers to the gastrointestinal mucosa by gastric acid and pepsin itself digestive ulcer, its depth to reach or penetrate the muscularis mucosa, the most common in gastric ulcer and duodenal ulcer, peptic ulcer (ulcer disease) It is a common chronic disease. Chinese literature reports, gastroscopy cases peptic ulcer detection rate as high as 16% to 33%. With the extensive development of gastroscopy, it is easy to diagnose and treat, but its treatment is relatively standard, but it has the characteristics of recurrent attack. Therefore, the study on the complete healing of ulcer disease has been paid more and more attention by clinicians. At present, the maintenance treatment with acid-suppressing drugs is to prevent peptic ulcer Recurrence of the main measures, but to maintain the treatment options, treatment time without a unified opinion.