目的对自体脂肪移植在乳房修复重建中的应用和研究进展作一综述。方法广泛查阅近年来采用自体脂肪移植进行乳房修复重建的相关文献,对乳房自体脂肪移植方法、术后效果和存在问题进行综述。结果乳癌术后可以选择自体脂肪移植修复重建乳房,该方法并发症少,虽然远期效果不稳定,但基本可以满足患者美容需求。目前自体脂肪移植的肿瘤安全性尚未明确,有待进一步研究。结论自体脂肪移植在乳房修复重建中获得了显著进展,但乳癌术后自体脂肪移植的肿瘤安全性仍需进一步研究。 Objective To summarize the application and research progress of autologous fat transplantation in breast reconstruction. Methods Extensive review of the recent literature on autologous fat transplantation for breast reconstruction and reconstruction of breast autologous fat transplantation methods, postoperative effects and existing problems are reviewed. Results Postoperative breast autologous fat transplantation can repair the reconstruction of the breast, the method less complications, although the long-term effect is not stable, but basically meet the cosmetic needs of patients. The current autologous fat transplantation tumor safety is not yet clear, pending further study. Conclusion Autologous fat transplantation has made significant progress in the repair and reconstruction of breast. However, the safety of autologous fat transplantation after breast cancer remains to be further studied.