NF-KappaB相关论文
研究背景前列腺癌目前是全世界常见的泌尿系统恶性肿瘤之一,虽然外科手术和去势治疗可以治疗部分前列腺癌,但部分肿瘤会继续复发和......
iASPP是一个众所周知的癌基因,而实验室先前的研究中发现,在细胞凋亡情况下,细胞质中的iASPP蛋白会被caspase-3蛋白剪切形成截短体......
Pingchuan formula (平喘方) improves allergic asthma in mice through inhibiting nuclear factor-kappa B/m
OBJECTIVE:To examine the role and decipher the mechanism of Pingchuan formula(平喘方,PCF)in treating allergic asthma.MET......
Ethanolic extract of Puhuang (Pollen Typhae) modulates lipopoly-saccharide-induced inflammatory resp
OBJECTIVE:To evaluate the immune modulatory response of Puhuang (Pollen Typhae),ethanolic ex-tract of dried pollens (TP-......
Grape-seed proanthocyanidins inhibit lipopolysaccharide-induced inflammatory mediators by suppressin
Proanthocyanindin extract is a mixture of polyphenols, mainly proanthocyanidins,obtained from grape seed with putative a......
VCAM-1 binding peptide conjugated DNA nanostructures for gene delivery to combat rheumatoid arthriti
Rheumatoid arthritis (RA) is a severe autoimmune disorder disease with chronic joint inflammation.NF-κB pathway is high......
Baicalein ameliorates LPS-induced acute lung injury in mice through Inhibition of inflammatory respo
Aim To study the effects of baicalein(BC), a phenolic flavonoid extracted mainly from Scutellaria baicalensis Georgi, on......
目的:通过比较大鼠运动模型中不同时间段NF-kB的表达特征,探索运动对海马神经适应过程的规律.方法:8周龄SD大鼠分为耐力训练组、未训......
会议
Sang-qi Granula Reduces Blood Pressure and Myocardial Fibrosis by Suppressing Inflammatory Responses
Aim: Sang-qi Granula (SQ) is a compound preparation of Chinese medcine and currently used for treatment of hypertension ......
An accumulating body of evidence suggests the significance of neuroinflammation with prolonged microglia activation and ......
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Pro-apoptotic role of NF-κB pathway inhibition in lipopolysaccharide-stimulated polymorphonuclear ne
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Pharmacological Inhibition of Macrophage Toll-like Receptor 4/Nuclear Factor-kappa B Alleviates Rhab
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目的 探讨β淀粉样蛋白(amyloid-β,Aβ)25-35诱导的大鼠嗜铬细胞瘤细胞(PC12)凋亡过程中核因子кB(nuclear factor кB,NF-кB)的......
目的:按国家药品注册法规的要求,考证古代经典名方百合地黄汤处方和制法及临床应用;揭示百合地黄汤古法制备的煎液化学物质构成;通过网......
OBJECTIVE:To explore the therapeutic effect and inflammatory mechanism of fire needles on gouty arthritis.METHODS:Sixty ......
Mechanism of apoptotic induction on T24 cells by honokiol and its synergistic anticancer effect in c
OBJECTIVE:To investigate the mechanism of hon-okiol (HNK) on bladder cancer cells and its synergis-tic anticancer effect......
边缘区淋巴瘤(MZL)是起源于边缘区的B细胞淋巴瘤,属于惰性淋巴瘤。MZL按照起源部位不同,分为3种亚型:黏膜相关淋巴组织(MALT)淋巴瘤、......
目的探究柚皮素(naringenin)对缺血再灌注(ischemia-reperfusion,IR)致急性肾损伤(acute kidney injury,AKI)的预防作用及其机制。方法为探......
目的 了解老年阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者中外周血单个核细胞(PBMC)的核因子-κB(NF-κB)活化及其致炎作用.方法 将40例......
目的 探讨核因子-κB(NF-κB)蛋白表达水平的变化与急性冠状动脉综合征(ACS)患者冠状动脉病变特征的关系.方法 初步诊断为冠心病并......
目的探讨罗格列酮对脂多糖(LPS)诱导的体外培养大鼠腹膜间皮细胞CD40和胞间黏附分子1(ICAM-1)表达的影响以及调节机制。方法分离及培养......
Xinfeng capsule improves pulmonary function in ankylosing spondylitis patients via NF-κB-iNOS-NO sig
OBJECTIVE: To study changes in the nuclear factor-κB p65(NF-κB p65)-inducible nitric oxide synthase(i NOS)-nitric oxid......
OBJECTIVE:To investigate the inhibitory effect of Jinghua Weikang capsule (JWC) on gastric inflammation induced by Helic......
Young Yum pill inhibits inflammatory mediators and nuclear factor-kappa B signaling in lipopolysacch
OBJECTIVE:To investigate the effect of Young Yum pill (YYP) on inflammatory mediators in cultured RAW 264.7 cells and el......
Regulation of Moxibustion on the Expression of NF-κBp65 and PPARγ mRNA in Colon of Rats with Ulcerat
Objective: To explore the mechanism of herb-partitioned moxibustion for ulcerative colitis (UC) through observing the co......
目的探讨大剂量去甲肾上腺素对感染性休克患者血流动力学、核转录因子κB(NF-κB)和人核因子κB抑制蛋白α(IκB-α)的影响。方法......
目的 了解燃煤砷暴露人群外周血T细胞活化情况及其外周血单个核细胞(PBMCs)内蛋白激酶C/核因子κB(PKC/NF-κB)途径相关信号分子的......
目的 探讨慢性氟中毒大鼠骨骼损伤时细胞核转录因子-κB(NF-κB)相关基因表达改变与破骨细胞凋亡的关系,深入研究氟骨症的发病机制......
目的通过观察核转录因子κB(NF-κB)p65在大骨节病患者全血和软骨细胞(C28/I2)中的表达,分析NF-κB p65分子在软骨细胞凋亡中的作用,阐明......
目的:探讨小泛素样修饰蛋白(SUMO)化修饰对核因子(NF)一KB通路激活的负性调控在2型糖尿病大鼠脑部病变中的干预作用,为前列地尔对......
目的:探讨舒洛地特对小泛素养修饰蛋白(SUMO)4介导的2型糖尿病大鼠肾脏功能的保护作用.方法:将20只GK大鼠按数字表法随机均分为糖......
目的 探讨重组慢病毒介导siRNA(小干扰RNA)靶向阻断NF-κB信号通路对人神经母细胞瘤QDDQ-NM1细胞侵袭转移的影响.方法 根据人p65基......
肝癌是患病率最高的恶性肿瘤之一,未来肝癌患病率和病死率将有逐步增长的趋势。核转录因子(NF-κB)能够通过介入多种途径,以达到影响......
目的 探讨乳胞素在诱导前列腺癌细胞凋亡作用中与核转录因子(NF)-κ B活性的关系.方法 利用乳胞素作用两种前列腺癌细胞,设立培养......
NF-κB转录因子家族广泛存在于真核细胞中,调控着细胞的生存、生长和凋亡过程,参与炎症、免疫性疾病及肿瘤等疾病的发生与发展。在大......
目的:检测肿瘤坏死因子-α(TNF-α)在慢性血吸虫病患者结肠组织中的表达变化,探讨血吸虫病对靶器官的损害,为评价血吸虫病的危害及血吸......
【目的】探讨赤芍801作用后的类风湿关节炎(rheumatoid arthritis ,RA )患者成纤维样滑膜细胞(Fibroblast-like synoviocytes ,FLS)p65和......
Zhuifeng tougu capsules(追风透骨胶囊)improve rheumatoid arthri-tis symptoms in rats by regulating the toll
OBJECTIVE:To investigate the efficacy of Zhuifeng tougu capsules(追风透骨胶囊,ZFTG)in the treat-ment of rheumatoid arthr......
OBJECTIVE: To investigate the efficacy of horse oil on lipopolysaccharide(LPS)-induced inflammation in human keratinocyt......
目的冠状动脉粥样硬化性心脏病(Coronary Heart Disease,CHD)是由冠状动脉粥样硬化(Atherosclerosis,As)导致的慢性缺血性心脏病,......
NF-kappa B通路是细胞内重要的炎症通路,近年来的研究发现它与癌症的发生和发展也有密切的关系,但许多方面仍存在许多值得探究的地......
学位
目的 :探讨鼻咽癌细胞中JIP抑制激活蛋白 1(AP - 1)信号转导途径的分子机制。方法 :用Dox诱导L7(Tet-on -LMP1-HNE2 )细胞表达LMP1......
期刊
目的:研究TRAIL诱导激素非依赖前列腺癌细胞株PC-3M过程中核因子kappa B(NF-κB)的活化和失活现象.方法:当不同浓度的TRAIL和LPS作......
目的 探讨血管紧张素Ⅱ(AngII)与核因子(NF)-κB、p38丝裂素活化蛋白激酶(p38MAPK)信号传导通路活化在人门静脉高压症(PHT)脾静脉......
目的 探讨异丙酚对大鼠离体心脏缺血再灌注时核因子κB(NF-κB)及诱导型一氧化氮合酶(iNOS)的影响.方法 成年SD大鼠24只,体重200~30......
放疗是食管癌的重要治疗手段,肿瘤细胞基因可能是决定放射效应韵一个关键因素。从放射损伤修复、细胞周期分布和信号转导三方面阐述......
目的 探讨核因子κB p65(NF-κB p65)表达变化与早产合并亚临床绒毛膜羊膜炎的关系.方法 选择2005年10月-2006年10月在湖南省人民......